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Heroin became notorious in the 1960s as an urban drug of abuse, but its resurgence is fueled by young people in rural and suburban areas, a study finds. Most first used prescription opioids.

"We don't face an existential crisis," the president told NPR in an exclusive interview. He said the U.S. is blessed with a growing economy and no prospect of war with another nation-state.

The study is the first to test an oral vaccine in the middle of an outbreak — in Guinea in 2012. And it offered a remarkable degree of protection against this deadly disease.

Apple's acquisition of the audio equipment and subscription streaming music service co-founded by Dre and record-producer Jimmy Iovine is the computer-maker's largest-ever such purchase.

Miles and Lyle Thompson are finalists for the Tewaaraton Award, college lacrosse's highest honor. Either would be the first Native to win it — an irony for a sport created by Natives.

Mental health programs are getting extra attention after the killing spree in California. A law in the state lets authorities require people to get treatment. But it's not clear whether it will help.

In his commencement address at West Point, President Obama laid out a range of goals. In an interview with Steve Inskeep, Obama discusses how he thinks he can use the time that he has left in office.

Amazon wants better terms for print and e-books and is refusing pre-orders for upcoming Hachette books, and slowing delivery for those already ordered. Authors are complaining on the Internet.

Gun violence in Chicago is so common in some neighborhoods that the daily reports of shootings can seem like little more than numbers. Our reporter saw the dangers of Chicago's South Side firsthand.

Search and salvage teams will assess where they should look next for the jet's remains after an Australian agency said the search area "can now be discounted as the final resting place of MH370."